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Lab News

2024

Our work demonstrating the role of IL-33 signaling and IL-4 during food allergy was just published in the journal Allergy. Citation: Mast cell responses in a mouse model of food allergy are regulated via a ST2/IL-4 axis; https://doi.org/10.1111/all.16257
Check out our most recent paper assessing the effects of IL-10 neutralization on mast cell responses during food allergy. Citation: IL-10 Neutralization Attenuates Mast Cell Responses in a Murine Model of Experimental Food Allergy; Immunohorizons (2024) 8 (6): 431–441. https://doi.org/10.4049/immunohorizons.2400002
Saurav Ranjitkar, Nicole Maldonado Perez and Caitlin Tedeschi presented their research at the AAI meeting in Chicago.
The lab's most recent paper investigating the role of IL-10 in IL-33-mediated mast cell activation was published in the Journal of Immunology. Citation: Ranjitkar et. al., IL-10 Differentially Promotes Mast Cell Responsiveness to IL-33, Resulting in Enhancement of Type 2 Inflammation and Suppression of Neutrophilia; https://doi.org/10.4049/jimmunol.2300884
Congratulations to Dr. Mathias and Nicole for receiving NIH supplemental funding in support of Nicole's graduate research.
Congratulations to Saurav Ranjitkar for receiving the AAI Trainee Poster Award (2024) from the American Association of Immunologists.
Congratulations to Dr. Mathias for receiving a grant from the CAHNR 2024 Equipment Grant Competition.
Saurav Ranjitkar, Nathan Jordan, and Olena Yatsechko presented their work at the Nutrition and Metabolism retreat at UConn Health.
Dr. Mathias presented the lab's research at the Nutrition and Metabolism retreat at UConn Health.

2023

Congratulations to Dr. Mathias for receiving a grant from the USDA to investigate the effects of plant polyphenols on protein disulfide isomerases in mast cells.
Welcome Saurav Ranjitkar, post-doctoral fellow, to the Mathias lab.
Dr. Mathias received a pilot grant from the Department of Nutritional Sciences to study transcriptional mechanisms by which IL-10 modulates mast cell activation during food allergy.
Welcome graduate students, Caitlin Tedeschi, Nicole Maldonado Perez, and Nathan Jordan to the Mathias lab.
Congratulations to Dr. Mathias (Co-PI ) and Dr. Blesso (PI) for receiving a grant from the American Egg Board to investigate effects of egg yolk sphingomyelin in the modulation of the gut-liver axis.
Dr. Mathias gave a seminar in the Department of Pathobiology at UConn
Congratulations to Dr. Mathias for receiving an NIH grant (RO1) aimed at examining the differential effects of IL-10 on mast cell-mediated allergic responses.

2022

Dr. Mathias gave a seminar in the Genomic and Mechanistic Metabolism series at UConn.
Welcome to undergraduate students, Olena Yatsechko, Krupal Patel, and Anjeli Joseph.
Dr. Mathias gave a seminar in the ImmunoCardio Metabolism series at UConn.
Dr. Mathias started at his lab in the Department of Nutritional Sciences at the University of Connecticut.